Has the Toxicity of Therapeutic Deep Eutectic Systems Been Assessed?

نویسندگان

چکیده

Therapeutic Deep Eutectic Systems (THEDESs) are a mixture of components, including an active pharmaceutical ingredient, that have recently emerged because their interesting properties for drug therapies. In general, they been recognized to increase the solubility and permeability some drugs, consequently, bioavailability. Moreover, also used novel formulations pharmaceuticals. Despite potential benefits THEDESs, concerns about safety toxicity remain. this review, we summarize previous studies investigated THEDESs. These evaluate THEDESs using various methods, cell cultures, animal models, human trials. The results findings suggest generally well-tolerated low toxicity. However, further research is needed fully understand long-term effects these systems on health identify any adverse effects.

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ژورنال

عنوان ژورنال: Applied sciences

سال: 2023

ISSN: ['2076-3417']

DOI: https://doi.org/10.3390/app13105980